KPV Peptide – Anti-Inflammatory & Immunomodulatory Research Compound | ≥98% Purity

KPV (Lysine–Proline–Valine) is a short-chain tripeptide derived from the C-terminal region of alpha-melanocyte-stimulating hormone (α-MSH). It is widely studied in laboratory settings for its potent anti-inflammatory and immunomodulatory properties, particularly in models involving inflammatory signaling, gut health, and immune response regulation.

Due to its small molecular structure and targeted activity, KPV has gained attention in research focused on cytokine modulation, inflammatory bowel conditions, and systemic inflammatory responses.

Mechanism of Action

KPV exerts its effects through modulation of inflammatory and immune-related pathways.

Cytokine Regulation

• Downregulates pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β
• Supports balanced immune signaling
• Reduces excessive inflammatory responses in research models

NF-κB Pathway Modulation

• Inhibits activation of nuclear factor kappa B (NF-κB)
• Reduces transcription of inflammatory mediators
• Supports cellular protection against inflammatory stress

Gut Barrier Support

• Investigated for its role in maintaining intestinal integrity
• Studied in models of inflammatory bowel conditions
• Supports epithelial repair and barrier function

Research Significance

KPV is commonly utilized in experimental models studying:

• Inflammatory bowel disease (IBD) and gut inflammation
• Cytokine signaling and immune modulation
• Chronic inflammatory conditions
• Skin inflammation and wound healing
• Systemic inflammatory response pathways

Its targeted anti-inflammatory activity makes it a valuable compound for research involving immune balance and inflammation control.

Key Research Applications

• Anti-inflammatory pathway research
• Cytokine modulation studies
• Gut health and intestinal integrity models
• Immune system regulation investigations
• Skin and tissue inflammation research
• Chronic inflammation and stress-response models

Product Specifications

• Form: Lyophilized peptide
• Purity: ≥98%
• Peptide Class: Anti-inflammatory tripeptide
• Sequence: Lys-Pro-Val (KPV)

(Available quantities may vary by batch.)

Storage & Handling

• Store lyophilized KPV peptide in a cool, dry environment protected from light.
• Reconstitute with bacteriostatic water prior to research use.
• After reconstitution, refrigerate and use within the recommended research timeframe.

Sold per vial. Requires bacteriostatic water for reconstitution.
For laboratory research use only. Not for diagnostic, therapeutic, or human consumption.